Glyconeurobiology: Glycans in Neuroscience

Carbohydrate rich molecules like including glycolipids, glycoproteins, and proteoglycans in the nervous system have important roles during development, regeneration and synaptic plasticity. The structural diversity of the carbohydrate moieties renders them ideally suited as stage-specific biomarkers for various cell types leading to mediate interactions between recognition molecules, thereby contributing to the formation of a complex molecular framework at the cell surface and in the extracellular matrix of the cell. The exceptional structural diversity of glycan chains and related moieties allows for immense advanced possibilities that can leads to cell interactions along with cell matrix interactions.

 

  • Neural cell adhesion molecules (NCAMs)
  • Neuroregenerative biomaterials
  • Glycans in signaling
  • Carbohydrate mimetics
  • Neurological disorders

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