Glycolipids and Glycopeptides

Glycolipids are limited in fractions but known to be major and important contributors of glycoconjugates in all areas of life. The structural diversity of glycolipids is exceptional, as different types of lipids are glycosylated in almost every forms of life like animals, plants, and bacteria. Their role basically is to maintain stability of the membrane and to facilitate other cellular recognition. They act as glycan-carriers in the membranes of photosynthetic structures in, algae, plants and bacteria.

Glycopeptides are basically peptides that contain carbohydrate moieties generally glycan’s which are covalently attached to the side chains of the amino acid residues that constitute the peptide. These include a class of drugs of microbial origin that are composed of glycosylated cyclic or polycyclic non ribosomal peptides.

 

  • Glycosyl transferases
  • Glycosyl mimetics
  • O-GlcNAc modification

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